Administration and dosing Cyanocobalamin is often injected intramuscularly or subcutaneously. If the medicine is given subcutaneously, take care not to inject it into the dermis or higher subcutaneous tissue. This will prevent its absorption into the blood stream.
Oral formulations of B12 are available but they must be taken with food supplements because they won't be absorbed properly without food. Also, people who suffer from stomach problems such as gastritis or gastroenteritis may not be able to absorb B12 through their digestive system. In this case, it's best if they receive an injection rather than try to take an oral dose.
Some studies have shown that injecting B12 directly into the bloodstream has some advantages over injecting it into the muscle. The liver plays a role in removing substances from the body by breaking them down into smaller molecules that can be removed through urine or expelled out of the body in bowel movements. By injecting B12 directly into the bloodstream, it gets sent directly to the liver where it is broken down before being released back into the blood stream. This means that fewer injections are needed over time as the body becomes more efficient at processing B12.
In conclusion, B12 needs to be injected intramuscularly or subcutaneously on regular intervals.
Cyanocobalamin and vitamin B12 injections are identical in all ways except for their names. Vitamin B12 is a general term for a group of compounds that play important roles in human health. There are two main forms of vitamin B12: cobalamin (cob) and cyanocobalamin (cyn). Injections of pure vitamin B12 can be used to treat deficiencies of this essential nutrient.
In addition to being good sources of protein, vitamin B12-rich foods include shrimp, salmon, meat products, milk products, and eggs. Meat products especially contain large amounts of this vital nutrient. It is also found in some plants, such as spinach and corn. However, the amount of vitamin B12 in these foods is usually too small to have any significant effect on blood levels of this vitamin. The only source of vitamin B12 that has been shown to affect blood levels of this vitamin is animal tissue. Thus, individuals who do not eat meat may require supplements if they are not getting enough B12 in their diet.
Vitamin B12 is needed for healthy blood cells to function properly.
However, the average intramuscular injection dosage is roughly 1,000 mcg each month. If you have a vitamin B12 deficiency, your doctor may prescribe 30 to 100 micrograms of cyanocobalamin daily for five to ten days. Maintenance dosages of 100 to 200 micrograms per month may also be necessary.
The oral dose recommended by most experts is 2.4 mg daily. This amount can be found in one capsule of methylcobalamin or hydroxycobalamin. A single dose of 5-10 mg cyanocobalamin has been used in patients with severe deficiencies. Higher doses up to 40 mg/day have been reported in cases studies.
The absorption rate of cyanocobalamin is approximately 10 percent. This means that out of every hundred milligrams ingested, only ten milligrams are available for use by the body. Oral supplements containing between 500 and 1,000 mcg per day have been used in clinical trials to treat patients with chronic disorders. However, higher doses have not been tested extensively and there may be adverse effects at these levels.
Cyanocobalamin is usually taken once a month by injection or orally once a week. The injections should be given about one month apart. It may take four months of continuous intake before any effects are seen. At least two months of continuous intake is required to show improvement in blood counts.
Cyanocobalamin is a manufactured version of vitamin B12 that can only be obtained through supplements, whereas methylcobalamin is a naturally occurring type that may be obtained from either diet or supplements. Cyanocobalamin is used in medicine while methylcobalamin is used primarily as a supplement to help increase levels of methionine in the body.
Cyanocobalamin has a molecular weight of 1,108.16. The chemical formula for cyanocobalamin is C60H102N2O5S. It consists of two parts: cyano means "blue" and co-baltuminoide means "vitamin B12".
Methylcobalamin has a molecular weight of 1,128.16. The chemical formula for methylcobalamin is C59H104N2O5S. It consists of two parts: methyl means "one-fifth" and cobalamin means "vitamin B12".
Vitamin B12 was first discovered by Albert Bender and Edwin Gierer in 1929. They named it "vita niacina" which translates into "niacin (B3) bacteria". Before this discovery, scientists believed that animals were the only organisms capable of making their own vitamin B12.