Antimicrobial medication is the sole treatment necessary in the majority of instances with actinomycosis, while surgery may be used in some circumstances. Penicillin G is the medication of choice for treating actinomycetes infections. Parenteral antibiotics are initially provided by PICC line, with oral drugs being added later. The antibiotic should be given for at least six months after all signs of infection have resolved. If penicillin is not available as an option, other antibiotics that work against actinomycetes include erythromycin, tetracycline, and clindamycin.
The primary therapy for actinomycosis is antibiotics. In most cases, high dosages of penicillin are required to cure the illness. If you are allergic to penicillin, your doctor may prescribe another antibiotic, such as tetracycline. Actinomycosis cannot be cured by simply stopping the treatment; instead, the infection must be treated with antibiotics for at least six months after all signs of the disease have disappeared.
Actinomycosis is a rare disease that can affect anyone. It may come back if not treated with antibiotics. Actinomycosis should be considered in the diagnosis of any patient who has recently undergone surgery or has an indwelling medical device such as a catheter or heart valve.
Actinomycosis is difficult to diagnose because it can look like many other diseases on physical examination. A biopsy is needed to confirm the diagnosis. Treatment includes antibiotics to kill any bacteria causing the problem along with removal of any remaining tissue containing the bacteria.
Actinomycosis is traditionally treated with high-dose intravenous penicillin at a dosage of 18–24 million units per day for 2–6 weeks, followed by oral penicillin or amoxicillin for 6–12 months [1, 2]. Surgery may be required to remove infected tissue or to relieve symptoms.
Because of the risk of severe side effects including heart damage and allergic reaction, most patients require blood cell counts and liver function tests while taking antibiotics. Actinomycosis should not be confused with mycotic infections such as candidiasis or histoplasmosis which need different treatments. If you are unsure whether your symptoms require treatment, consult with your doctor.
Actinomycosis is an uncommon infectious condition that occurs when bacteria travel from one place of the body to another via bodily tissues. It can lead to associated abscesses, discomfort, and inflammation over time. It can damage the skin, deeper regions of the body, and, in certain cases, the blood. Actinomycosis usually results from infection by a group of organisms called "actinomycetes." The disease was first described by French physician Pierre Marie in 1768.
Actinomycosis affects people of all ages but is more common in adults aged 50-60 than in children. It is more likely to occur in women than men. Factors such as diabetes, heart disease, cancer, immunosuppression, and alcoholism may increase your risk of developing actinomycosis.
In actinomycosis, the bacteria invade and infect tissue cells, causing localized areas of destruction known as abscesses. If not treated, actinomycosis can spread throughout the body, leading to life-threatening conditions. Actinomycosis can affect any part of the body, but most cases involve the lungs, abdomen, breast tissue, groin, and reproductive organs. It is rare for actinomycosis to spread beyond these areas.
Diagnosing actinomycosis requires a biopsy because its symptoms are similar to those of many other diseases.
Actinomycosis is a chronic (long-term) bacterial infection that most typically affects the face and neck. It may also affect other parts of the body, including the chest, abdomen, and reproductive organs. Actinomycosis is rare but important to recognize because it can be confused with many other conditions that present with similar symptoms.
The disease was first described by Drs. William Coley and Simon Brodie in 1873. They called it "mycotic arthritis" because they believed the bacteria to be fungi. Later studies showed that this organism does not produce spores nor is it actually a fungus; therefore, this term is no longer used.
Actinomycosis occurs when normal oral flora such as streptococci or anaerobic bacteria are able to invade and colonize the tissues of the mouth. These organisms may enter the body through tiny breaks in the skin or via the lymph system. If enough tissue is invaded, then pain, swelling, and eventually deformity may occur.
The condition is more common in individuals who have decreased immune function due to diseases such as AIDS or cancer or take immunosuppressive medications. However, anyone can get actinomycosis if the right conditions are present.