Can I take isoniazid alone?

Can I take isoniazid alone?

Rifampin, isoniazid, and pyrazinamide are used to treat tuberculosis (TB) infection. It can be used alone or in combination with one or more other TB medications. Rifampin is the most important drug in the treatment regimen.

Isoniazid can cause liver problems that lead to death. Therefore, you should not use isoniazid if you have severe liver disease or diabetes. You also should not use isoniazid if you are taking carbamazepine or phenytoin because these drugs can cause serious side effects including suicidal thoughts and behavior when taken with isoniazid.

Isoniazid must be taken for six months to prevent recurrence of TB. This is followed by a two-month period during which time you continue to take rifampin to prevent new infections. Isoniazid may need to be taken for life after successful treatment of active TB.

Isoniazid is safe with most other medications without any special warnings except that you should not take it within 14 days of stopping oral contraceptives because it can cause fetal damage.

If you are taking isoniazid for more than six months, your doctor will likely start you off on a low dose and slowly increase it over time. The maximum recommended dose is 300 mg per day.

What medications can you not take with amitriptyline?

During therapy with this drug, do not use MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine). Most MAO inhibitors should also be avoided for two weeks before to and following therapy with this drug. This is important because major depression is often accompanied by anxiety or panic attacks. By reducing levels of norepinephrine and serotonin in the brain, amitriptyline may increase sensitivity to stressors which could lead to suicidal thoughts or actions.

Do not use this drug if you are pregnant or may become pregnant. Do not give it to anyone under 18 years of age. It may cause birth defects or other problems if taken by women who are pregnant or think they might be pregnant. Stop taking it and call your doctor at once if you experience any symptoms such as dizziness, faintness, trouble breathing, chest pain, or heart failure.

Amantriptyline is used to treat depression. It works by blocking the action of certain chemicals in the brain that cause depression. It must be taken every day for it to be effective and there are concerns about using it long-term due to its effect on the stomach. However, it may be necessary to take amitriptyline for several months to achieve complete relief from symptoms.

Amitriptyline is available only through your doctor - it must be prescribed by a physician.

How long should you take artemisinin?

Coartem, a combination of artemether (20 mg) and lumefantrine (120 mg), was licensed for the treatment of P. falciparum malaria in the United States in 2009. Adults should take 4 pills twice daily for three days (6 doses). Children should take two pills twice daily for four days (8 doses). The medication is safe when taken as directed but may cause some side effects such as nausea, vomiting, diarrhea, stomach pain, rash, or dry skin.

Artemisinins work by triggering a rapid breakdown of hemoglobin inside the parasite's digestive system resulting in its death. The drugs are effective against all stages of the malaria parasite. Treatment with artemisinins results in a cure rate of more than 95% if it is given properly. However, without proper treatment, the disease will likely return.

There are several factors that may affect how fast you recover after taking artemisinin medications. Your health before you got sick with malaria, the type of malaria you have, and how many parasites are in your blood can all influence how quickly you recover. The length of time you remain free of symptoms after starting therapy also depends on how many parasites are in your body when you first see a doctor. If you start treatment early, the majority of people make a full recovery within 14 days. However, if you wait until after being infected for several weeks to begin treatment, you risk developing complications from the disease.

Why is vitamin B6 given with isoniazid?

Vitamin B6 (pyridoxine) supplementation during isoniazid (inh) medication is required in some patients to avoid the development of peripheral neuropathy and vitamin deficiencies in persons with a risk factor, such as pregnancy, breastfeeding, HIV infection, alcoholism, diabetes,...

What is the antidote for isoniazid?

Pyridoxine is the isoniazid antidote. If it is suspected that the status epilepticus is the consequence of isoniazid toxicity, pyridoxine should be administered as soon as feasible. Isoniazid inhibits NADH dehydrogenase, an enzyme necessary for the production of energy within cells. Inhibition of this enzyme causes cell death. The median time to onset of symptoms after isoniazid ingestion is 5 days. However, some patients may not develop symptoms for up to 26 days after ingestion.

Isoniazid therapy should be discontinued if seizure activity continues despite treatment with anticonvulsants. Discontinuation of isoniazid can lead to resolution of the adverse effects associated with isoniazid therapy and prevention of further hepatotoxicity. Isoniazid can cause severe liver damage or failure if not treated promptly when symptoms occur. Symptoms of isoniazid-induced hepatitis include fever, fatigue, nausea, vomiting, diarrhea, abdominal pain, dark urine, decreased smell and taste perception, jaundice, eyesight changes (particularly blurred vision), muscle aches, headache, confusion, or mood changes (including anxiety, depression). If you are taking any other medications, check with your doctor before you start isoniazid to make sure that you do not have any interactions with each other.

About Article Author

Louise Peach

Louise Peach has been working in the health care industry for over 20 years. She has spent most of her career as a Registered Nurse. Louise loves what she does, but she also finds time to freelance as a writer. Her passions are writing about health care topics, especially the latest advances in diagnosis and treatment, and educating the public about how they can take care of their health themselves.

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